• animal testing alternatives
• animal experiments
• animal welfare
• laboratory animals
• germfree animals
• gnotobiotic animals
• laboratory mammals
• experimental design
• laboratory tests
• research
• culture techniques
• cell culture
• in vitro culture
• somatic embryogenesis
• tissue culture
• controls (experimental)
• case-control studies
• methodology
• models
• animal models
• disease models
• genetic models
• growth models
• mathematical model
• simulation models
• euthanasia
• animal housing (explode; lots of terms included)
• animal husbandry (also consider related terms)
• restraint of animals
• fencing
• tethering
• pain
• anaesthesia
• conduction anaesthesia
• local anaesthesia

• animal experimentation
• animal use alternatives
• animal testing alternatives
• vivisection
• animal welfare
• animal care committees
• animal rights
• chronic pain
• models, animal
• disease models, animal
• models, theoretical
• models, biological
• disease models, animal
• models, cardiovascular
• models, genetic
• models, immunologic
• models, neurologic
• models, molecular
• research design
• control groups
• sample size
• case-control studies
• retrospective studies
• euthanasia
• euthanasia, active
• euthanasia, passive
• animals, laboratory
• animals, congenic
• animals, inbred strains
• housing, animal
• animal husbandry
• immobilization
• restraint physical
• hindlimb suspension
• culture techniques
• cell culture techniques
• organ culture techniques
• tissue culture techniques
• pain (explode; lots of terms included)
• anesthesia and analgesia (explode; lots of terms included; method of delivery not the drugs)

3 R's: Reduction, Refinement, Replacement

• advers*
• alternative
• analges*
• anesthe* anasthe*, anaesthe*
• animal testing alternative*
• anxiolytic painkiller sedative tranquilizer
• artificial simulate*
• assay* technique*, method*, procedur*
• cadaver*
• culture* (cell, tissue, organ)
• environment* enrich*
• euthanasia euthani?e
• handling immobilize restrain restrict
• housing, cage caging
• Invasive non-invasive
• invertebrate*
• isolated (cell, tissue, organ)
• mannequin or manikin
• monitor* device*
• model* experimental design
• pain*, distress* stress* relieve* relief
• plastinat*
• positive reinforce*
• postoperative postsurgery
• refine*
• replace*
• restrain*, immobil*
• restrict*
• software
• technique*, method*, procedur*
• train*, educat*, teach*, instruct*
• video*
• virtual (surgery, reality)
• vitro (method, model, technique)
• welfare well-being humane